3 file types use the .pxi file extension.

What is a PXI file?

A PXI file is a source code file written in Pyrex, a programming language designed to help developers write Python modules that include C-level performance code. Developers primarily use PXI files to store chunks of code to be inserted into a .PYX file, allowing them to reuse code or break large modules into smaller, more manageable parts.

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How to open a PXI file

Category: Developer Files

PlexTools Disc Image

A PXI file may also be a disc image created by Plextor PlexTools, a now-discontinued disc copying and management program bundled with Plextor CD and DVD drives. It contains an exact copy of the data from a CD or DVD, including files, folders, and disc structure. Users typically created PXI files to back up physical discs or to make duplicate copies of discs.

PlexTools was a suite of CD and DVD management tools developed by Plextor, a company known for its high-quality optical drives . Plextor released the program in the early 2000s to work exclusively with Plextor drives, offering advanced features like disc copying, audio extraction, drive diagnostics, and media quality testing.

It was often bundled with Plextor hardware and became a favorite among users who wanted greater control over their optical media and drive performance. Plextor eventually discontinued PlexTools, making the PXI format obscure as physical media declined.

You can open PXI files with EZB Systems UltraISO or Smart Projects IsoBuster in Windows. You can also open PXI files with Plextor PlexTools Professional software, but it is discontinued.

Several programs, including Smart Projects IsoBuster and EZB Systems UltraISO, can convert PXI files to other file types. For example, IsoBuster can convert PXI files to the .ISO Disk Image format.

Programs that open PXI files

Updated: May 7, 2025

Pixen Image

A PXI file may also be the native image format used by Pixen, a pixel art editor developed for macOS by Furnace Creek Software. It stores all the components of an art project, including image layers and their elements, such as shapes, colors, and brush strokes. The PXI format enables users to save their work, then return to it later and continue editing with full access to layers and settings.

Artists use Pixen to create detailed pixel-based artwork, animations, and game assets. The PXI format is particularly useful for artists working on complex or multi-frame images, such as character sprites or animated tiles used in video games.

The PXI format is similar to Adobe Photoshop's .PSD format, allowing users to edit their artwork non-destructively so they can make changes without altering the original layers. Because PXI files store editable project data, users must export them to a standard image format before using them in games or on websites.

You can open a PXI file with Furnace Creek Software Pixen. To open a PXI file with Pixen, select File → Open .

Pixen can convert PXI files to various types of image formats, including the following:

The free version of Pixen can only convert PXI files to JPEG or PNG format. The Pro version is required to convert to the other formats.

Programs that open PXI files

Updated: July 9, 2025